On Optimal Therapy Protocols in the Mathematical Model of Prostate Cancer Progression

Authors

  • Marie-Christin Litzinger University of Applied Sciences, Mannheim, Germany
  • Y. Todorov University of Applied Sciences, Mannheim, Germany
  • Miriam Foller-Nord University of Applied Sciences, Mannheim, Germany
  • Manitjaiswal K. Chaudhary Nikolsky Mathematical Institute, Rudn University, Moscow, Russia
  • Alexander S. Bratus Russian University of Transport, Moscow, Russia; Moscow Center of Fundamental and Applied Mathematics, Moscow, Russia

DOI:

https://doi.org/10.25728/assa.2020.20.4.998

Keywords:

prostate cancer, androgen ablation, therapy strategies, optimal control, state constraint

Abstract

A mathematical model for the treatment of prostate cancer regarding androgen ablation is considered. The effect of the therapy on healthy cells is taken into account and modelled as a second order state constraint. A mathematical overview about possible therapy strategies is presented.

Downloads

Published

2021-01-01

Issue

Vol. 20 No. 4 (2020): Advances in Systems Science and Applications

Section

Articles

How to Cite

On Optimal Therapy Protocols in the Mathematical Model of Prostate Cancer Progression. (2021). Advances in Systems Science and Applications, 20(4), 83-104. https://doi.org/10.25728/assa.2020.20.4.998