On Optimal Therapy Protocols in the Mathematical Model of Prostate Cancer Progression

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Published Jan 1, 2021
DOI https://doi.org/10.25728/assa.2020.20.4.998

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Marie-Christin Litzinger
University of Applied Sciences, Mannheim, Germany
Y. Todorov
University of Applied Sciences, Mannheim, Germany
Miriam Foller-Nord
University of Applied Sciences, Mannheim, Germany
Manitjaiswal K. Chaudhary
Nikolsky Mathematical Institute, Rudn University, Moscow, Russia
Alexander S. Bratus
Russian University of Transport, Moscow, Russia; Moscow Center of Fundamental and Applied Mathematics, Moscow, Russia

Abstract

A mathematical model for the treatment of prostate cancer regarding androgen ablation is considered. The effect of the therapy on healthy cells is taken into account and modelled as a second order state constraint. A mathematical overview about possible therapy strategies is presented.

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How to Cite
Litzinger, M.-C., Todorov, Y., Foller-Nord, M., Chaudhary, M., & Bratus, A. (2021). On Optimal Therapy Protocols in the Mathematical Model of Prostate Cancer Progression. Advances in Systems Science and Applications, 20(4), 83-104. https://doi.org/10.25728/assa.2020.20.4.998
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Vol 20 No 4 (2020): Advances in Systems Science and Applications
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Articles